Search / Trial NCT00001515

Diagnostic Effectiveness of Virtual Bronchoscopy

Launched by NATIONAL INSTITUTES OF HEALTH CLINICAL CENTER (CC) · Nov 3, 1999

Trial Information

Current as of December 06, 2024

Completed

Keywords

Wegener's Granulomatosis Computer Assisted Visualization Lung Cavities Endobronchial Lesions Computed Tomography (Ct) Bronchogenic Carcinoma

ClinConnect Summary

This project is a test of the efficacy of a new diagnostic method for imaging the airways known as virtual bronchoscopy. Virtual bronchoscopy is performed by acquiring thin section computed tomography (CT) images of the chest. These images are used to generate a three dimensional model of the tracheal and bronchial walls on a graphics workstation in 3-D. The model can be manipulated to allow the viewer to "fly through" the tracheobronchial tree providing views similar to those obtained during bronchoscopy. The technique produces a display of the human bronchial system in a readily understoo...

Gender

ALL

Eligibility criteria

  • Patients with Wegener's granulomatosis who are scheduled for fiberoptic bronchoscopy.
  • Patients with cavitary lung diseases who are enrolled in protocols studying patients with Wegener's granulomatosis, chronic granulomatosis disease, host immune defects, mycobacterial infections, and Job's syndrome.
  • Patients with bronchogenic carcinoma, other thoracic malignancies, or metastatic disease to the thorax.
  • Patients will be selected from Clinical Center inpatient and outpatient population based on a clinical suspicion of pulmonary, mediastinal or bronchial disease, and are to have medically indicated chest CT.
  • Written informed consent will be obtained from all patients and studies will only be done with the permission of the patient's attending physician.
  • Patients will be drawn from the following protocols:
  • 92-I-0186
  • 93-I-0119
  • 94-I-0149
  • 95-I-0091
  • 90-I-0086
  • 76-I-0023
  • 92-I-0255
  • 93-I-0172
  • 95-I-0177
  • Subjects must not be pregnant and be able to hold their breath for required periods of time.

About National Institutes Of Health Clinical Center (Cc)

The National Institutes of Health Clinical Center (CC) is the nation's largest hospital dedicated exclusively to clinical research, serving as a pivotal facility for advancing medical knowledge and innovative therapies. Located in Bethesda, Maryland, the Clinical Center provides a unique environment where patients have access to cutting-edge treatments and participate in groundbreaking clinical trials across a wide range of diseases. As a leader in translational research, the CC integrates patient care with scientific investigation, fostering collaboration among researchers, clinicians, and patients to accelerate the development of new interventions and improve health outcomes.

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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