Diagnostic Effectiveness of Virtual Bronchoscopy

Launched by NATIONAL INSTITUTES OF HEALTH CLINICAL CENTER (CC) · Nov 3, 1999

Keywords

ClinConnect Summary

This project is a test of the efficacy of a new diagnostic method for imaging the airways known as virtual bronchoscopy. Virtual bronchoscopy is performed by acquiring thin section computed tomography (CT) images of the chest. These images are used to generate a three dimensional model of the tracheal and bronchial walls on a graphics workstation in 3-D. The model can be manipulated to allow the viewer to "fly through" the tracheobronchial tree providing views similar to those obtained during bronchoscopy. The technique produces a display of the human bronchial system in a readily understoo...

Gender

ALL

Eligibility criteria

• • Patients with Wegener's granulomatosis who are scheduled for fiberoptic bronchoscopy.
• • Patients with cavitary lung diseases who are enrolled in protocols studying patients with Wegener's granulomatosis, chronic granulomatosis disease, host immune defects, mycobacterial infections, and Job's syndrome.
• • Patients with bronchogenic carcinoma, other thoracic malignancies, or metastatic disease to the thorax.
• • Patients will be selected from Clinical Center inpatient and outpatient population based on a clinical suspicion of pulmonary, mediastinal or bronchial disease, and are to have medically indicated chest CT.
• • Written informed consent will be obtained from all patients and studies will only be done with the permission of the patient's attending physician.
• Patients will be drawn from the following protocols:
• • 92-I-0186
• • 93-I-0119
• • 94-I-0149
• • 95-I-0091
• • 90-I-0086
• • 76-I-0023
• • 92-I-0255
• • 93-I-0172
• • 95-I-0177
• • Subjects must not be pregnant and be able to hold their breath for required periods of time.