Genetic Factors Related to Stuttering
Launched by NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS (NIDCD) · Nov 3, 1999
Trial Information
Current as of May 09, 2025
Completed
Keywords
ClinConnect Summary
Genetic studies in developmental stuttering are important for their potential in ultimately determining pathophysiological basis of this disorder. This study will combine two approaches to examine genetic aspects of stuttering, linkage in families, and candidate gene analysis. Linkage studies will be completed using adult individuals who are diagnosed as persons who stutter and those who can be judged as never having stuttered from one or more families with large numbers of affected individuals within several generations. Candidate gene analyses will also be carried out in adults who stutte...
Gender
ALL
Eligibility criteria
- INCLUSION CRITERIA:
- • Subjects must be over the age of 5 and under the age of 90.
- • Subjects must be in general good health, without evidence of chronic medical illness.
- • Onset of stuttering in affected individuals must have occurred in childhood (between 3 and 10 years of age), unrelated to psychological or neurological trauma.
- • Subjects will not be tested for the presence of HIV antibodies. Persons with positive HIV antibodies will not be excluded, unless they are taking medication which may change their performance on tasks used for phenotypic assignment.
- • Subjects will be screened for history of psychiatric illness, such as depression, anxiety or obsessive-compulsive disorders according to DSM-IV criteria. A history of these disorders will not disqualify any subject from participation, but will be noted as a variable in phenotypic assignment.
About National Institute On Deafness And Other Communication Disorders (Nidcd)
The National Institute on Deafness and Other Communication Disorders (NIDCD) is a prominent agency within the National Institutes of Health (NIH) dedicated to advancing research and understanding of hearing, balance, taste, smell, voice, speech, and language disorders. Through rigorous clinical trials and innovative research initiatives, the NIDCD aims to improve the diagnosis, treatment, and prevention of communication disorders, ultimately enhancing the quality of life for individuals affected by these conditions. The institute fosters collaboration among researchers, healthcare professionals, and patients to translate scientific discoveries into effective clinical practices and public health strategies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bethesda, Maryland, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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