Study of the Composition of Dental Plaque
Launched by NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH (NIDCR) · Nov 3, 1999
Current as of March 02, 2024
Dental caries and periodontal disease are closely associated with dental plaque, the biofilm that results from microbial colonization of the tooth surface. Various experimental models have been described for the initial phase of colonization, including one that utilizes enamel chips positioned within the oral cavity for periods of time up to 24 hours. Scanning electron microscopy of chips removed after 4 hrs in vivo revealed individual bacteria attached to the pellicle-coated surface. Growth of these pioneer organisms resulted in microcolonies that merged to form a spreading monolayer of co...
- INCLUSION CRITERIA:
- Aged 18 to 65 years
- EXCLUSION CRITERIA:
- History of medical conditions affecting salivary flow.
- History of immunosuppressant therapy.
- Use of tobacco.
- Use of antibiotics within the preceding four months.
- Use of medications thought to affect salivary flow.
- Missing any maxillary premolar, first, or second molar.
- Unwilling or unable to give informed consent.
The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States
All reviews come from applied patients