Search / Trial NCT00001776

Effects of Brain Stimulation on Learning and Reasoning

Launched by NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (NINDS) · Nov 3, 1999

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Trial Information

Current as of July 14, 2024

Completed

Keywords

Magnetic Stimulation Plasticity Srtt Sequence Implicit Memory Explicit Memory Memory Parkinson's Disease Cerebellar Deficit Frontal Lobe Lesions Frontal Lobe Dementia Normal Volunteer

Description

The human frontal cortex subserves a number of psychological processes including those necessary for adequate implicit learning of visuomotor sequences and analogical reasoning. Implicit learning is a form of procedural learning indicated by behavioral improvement without awareness of a repeated stimulus structure that leads to improved performance. This type of learning has been associated with activation of the primary motor cortex (M1) in neuroimaging studies. While neuroimaging studies contributed to identify this region, they do not provide information about its relative role in the p...

Gender

All

Eligibility criteria

  • INCLUSION CRITERIA
  • Right handed normal volunteers (18-65 years old).
  • Patients with Parkinson's disease off medication.
  • Patients with cerebellar deficits.
  • Patients with frontal lobe lesions.
  • Patients with frontal lobe dementia.
  • EXCLUSION CRITERIA
  • Subjects with personal or family history of seizures or other neurological disorders.
  • Pregnant women.
  • Volunteers or patients with severe coronary artery disease.
  • Metal in the cranium except mouth.
  • Intracardiac lines.
  • Increased intracranial pressure as evaluated by clinical means.
  • Cardiac pacemakers.
  • Intake of neuroleptics.

Attachments

readout_NCT00001776_2024-07-14.pdf

4.5 MB

NCT00001776_study_protocol.pdf

4.5 MB

About company

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Bethesda, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Reviews (48)

4.6

All reviews come from applied patients

5 stars
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Leslie Alexander
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Michael Foster
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Dries Vincent
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Leslie Alexander
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

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