Live Donors for Kidney Transplants

Launched by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) · Nov 3, 1999

Keywords

ClinConnect Summary

This protocol is designed to facilitate the enrollment of healthy individuals to serve as renal allograft donors for subjects undergoing protocol renal transplantation at the NIH. Donation will be allowed for altruistic purposes only.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• • Willingness to donate without evidence of secondary gain, coercion, or conflict of interest.
• • Age greater than or equal to 18 years
• • ABO compatible with recipient
• • Normal renal function with a 24hr creatinine clearance greater than 80ml/min/1.73m(2).
• • Willingness and legal ability to give informed consent
• • Recipient is enrolled in a NIH protocol for transplantation or has been established as a candidate for receipt of an altruistic or paired donation through the Washington Regional Organ Procurement Agency donor program.
• EXCLUSION CRITERIA:
• • Hypertension
• • Pregnancy
• • History of stroke
• • Active tuberculosis
• • History of active malignancies except basal cell carcinoma of the skin.
• • Major anticipated illness or organ failure incompatible with survival after nephrectomy
• • Functionally significant coronary artery disease.
• • Active kidney stones
• • Proteinuria (greater than 250mg/24hr)