Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome

Launched by NATIONAL HUMAN GENOME RESEARCH INSTITUTE (NHGRI) · Dec 9, 2002

Keywords

ClinConnect Summary

Ehlers-Danlos Syndrome (EDS) encompasses a spectrum of connective tissue diseases thought to result from defects in collagen formation. People with EDS are often affected by chronic, progressive pain poorly responsive to conventional treatment. We propose to investigate the efficacy of mind-body therapy for treatment of chronic pain in Ehlers-Danlos Syndrome. A cohort of adult subjects will be treated with mind-body therapy in a pilot study to assess the efficacy and acceptability of this treatment modality. The primary outcome measure will be change in pain as scored with a standardized in...

Gender

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Eligibility criteria

• • Clinical diagnosis of classical or hypermobile EDS based on history and physical examination by a study investigator.
• • Subjectively suffer from chronic pain (defined as pain occurring at least weekly).
• • Must agree to not seek mind-body therapy or other similar interventions outside of this study during the time under investigation.
• • Able to give informed consent.
• • No minors (under 18 years of age).
• • Not currently using formal mind-body or similar therapy for treatment of chronic pain.
• • No major surgical procedure within 90 days or intending to undergo such a procedure during the time course of this study.
• • Not decisionally impaired subjects.
• • No previous diagnosis or hospitalization for a psychotic condition(s). Specifically, no history of illness involving altered perception of reality. Psychiatric diagnoses such as depression or anxiety will not exclude participation.