Immune System Related Kidney Disease

Launched by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) · Jan 20, 2000

Keywords

ClinConnect Summary

This clinical trial is focused on understanding kidney diseases that are linked to the immune system, such as nephrotic syndrome and lupus nephritis. Researchers are looking to admit patients who have these autoimmune kidney diseases or have immune system diseases that could lead to kidney problems. The goal is to gather information about the causes and specific features of these conditions, which may help in developing better treatments in the future.

To participate, individuals must be at least 10 years old, and they should have a known or suspected immune-related kidney disease. During the study, patients will undergo a thorough examination, including a review of their medical history and standard lab tests. These tests will help researchers learn more about the signs and symptoms of their kidney issues and how they respond to medications. Participants may also be asked to provide blood or urine samples throughout the study for additional research. It's important to note that some individuals might not be eligible if they have other medical conditions that could complicate the study results.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• In order to be eligible to participate in this study, a participant must meet all of the following criteria:
• • 1. Adults \>= 18 years of age and children 10-17 years of age
• • 2. Participants with
• • 1. known, proven, or suspected immunologically-mediated kidney diseases, including but not limited to nephrotic syndrome, glomerulonephritis, membranous nephropathy, lupus nephritis, and nephritis associated with other systemic or connective tissue disorders, OR
• • 2. immunologically-mediated diseases with the potential for kidney disease.
• • 3. Ability of the participant or guardian to understand and the willingness of the participant or guardian to provide written informed consent.
• EXCLUSION CRITERIA:
• An individual who meets any of the following criteria will be excluded from participation in this study:
• • 1. Concomitant medical problems which would confound the interpretation of studies of the immunologic kidney disorder.
• • 2. Concomitant medical, surgical, or other conditions for which inadequate facilities or funds are available to support their care at the NIH.