Nctid:
NCT00001981
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-12-04"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D010911", "term"=>"Pituitary Neoplasms"}, {"id"=>"D000172", "term"=>"Acromegaly"}], "ancestors"=>[{"id"=>"D010900", "term"=>"Pituitary Diseases"}, {"id"=>"D007027", "term"=>"Hypothalamic Diseases"}, {"id"=>"D001927", "term"=>"Brain Diseases"}, {"id"=>"D002493", "term"=>"Central Nervous System Diseases"}, {"id"=>"D009422", "term"=>"Nervous System Diseases"}, {"id"=>"D004700", "term"=>"Endocrine System Diseases"}, {"id"=>"D001849", "term"=>"Bone Diseases, Endocrine"}, {"id"=>"D001847", "term"=>"Bone Diseases"}, {"id"=>"D009140", "term"=>"Musculoskeletal Diseases"}, {"id"=>"D006964", "term"=>"Hyperpituitarism"}, {"id"=>"D004701", "term"=>"Endocrine Gland Neoplasms"}, {"id"=>"D009371", "term"=>"Neoplasms by Site"}, {"id"=>"D009369", "term"=>"Neoplasms"}, {"id"=>"D007029", "term"=>"Hypothalamic Neoplasms"}, {"id"=>"D015173", "term"=>"Supratentorial Neoplasms"}, {"id"=>"D001932", "term"=>"Brain Neoplasms"}, {"id"=>"D016543", "term"=>"Central Nervous System Neoplasms"}, {"id"=>"D009423", "term"=>"Nervous System Neoplasms"}], "browseLeaves"=>[{"id"=>"M13802", "name"=>"Pituitary Neoplasms", "asFound"=>"Pituitary Neoplasms", "relevance"=>"HIGH"}, {"id"=>"M13791", "name"=>"Pituitary Diseases", "relevance"=>"LOW"}, {"id"=>"M3531", "name"=>"Acromegaly", "asFound"=>"Acromegaly", "relevance"=>"HIGH"}, {"id"=>"M10077", "name"=>"Hypothalamic Diseases", "relevance"=>"LOW"}, {"id"=>"M5204", "name"=>"Brain Diseases", "relevance"=>"LOW"}, {"id"=>"M5742", "name"=>"Central Nervous System Diseases", "relevance"=>"LOW"}, {"id"=>"M7862", "name"=>"Endocrine System Diseases", "relevance"=>"LOW"}, {"id"=>"M5126", "name"=>"Bone Diseases", "relevance"=>"LOW"}, {"id"=>"M5128", "name"=>"Bone Diseases, Endocrine", "relevance"=>"LOW"}, {"id"=>"M12097", "name"=>"Musculoskeletal Diseases", "relevance"=>"LOW"}, {"id"=>"M7863", "name"=>"Endocrine Gland Neoplasms", "relevance"=>"LOW"}, {"id"=>"M10079", "name"=>"Hypothalamic Neoplasms", "relevance"=>"LOW"}, {"id"=>"M17887", "name"=>"Supratentorial Neoplasms", "relevance"=>"LOW"}, {"id"=>"M5209", "name"=>"Brain Neoplasms", "relevance"=>"LOW"}, {"id"=>"M12367", "name"=>"Nervous System Neoplasms", "relevance"=>"LOW"}, {"id"=>"M18937", "name"=>"Central Nervous System Neoplasms", "relevance"=>"LOW"}, {"id"=>"T139", "name"=>"Acromegaly", "asFound"=>"Acromegaly", "relevance"=>"HIGH"}], "browseBranches"=>[{"name"=>"Neoplasms", "abbrev"=>"BC04"}, {"name"=>"Nervous System Diseases", "abbrev"=>"BC10"}, {"name"=>"Gland and Hormone Related Diseases", "abbrev"=>"BC19"}, {"name"=>"All Conditions", "abbrev"=>"All"}, {"name"=>"Musculoskeletal Diseases", "abbrev"=>"BC05"}, {"name"=>"Rare Diseases", "abbrev"=>"Rare"}]}}, "protocolSection"=>{"designModule"=>{"studyType"=>"OBSERVATIONAL", "designInfo"=>{"timePerspective"=>"PROSPECTIVE", "observationalModel"=>"COHORT"}, "enrollmentInfo"=>{"type"=>"ACTUAL", "count"=>117}}, "statusModule"=>{"overallStatus"=>"COMPLETED", "startDateStruct"=>{"date"=>"1991-10-02", "type"=>"ACTUAL"}, "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2020-11", "completionDateStruct"=>{"date"=>"2020-11-20", "type"=>"ACTUAL"}, "lastUpdateSubmitDate"=>"2020-11-24", "studyFirstSubmitDate"=>"2000-01-21", "studyFirstSubmitQcDate"=>"2000-01-21", "lastUpdatePostDateStruct"=>{"date"=>"2020-11-27", "type"=>"ACTUAL"}, "studyFirstPostDateStruct"=>{"date"=>"2000-01-24", "type"=>"ESTIMATED"}, "primaryCompletionDateStruct"=>{"date"=>"2020-11-20", "type"=>"ACTUAL"}}, "outcomesModule"=>{"primaryOutcomes"=>[{"measure"=>"resolution of IGF-1 Growth Hormone abnormality", "timeFrame"=>"every 6 months & at end of study", "description"=>"resolution of IGF-1 abnormality"}]}, "conditionsModule"=>{"keywords"=>["Acromegaly"], "conditions"=>["Acromegaly", "Pituitary Neoplasm"]}, "referencesModule"=>{"seeAlsoLinks"=>[{"url"=>"https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_1985-DK-0082.html", "label"=>"NIH Clinical Center Detailed Web Page"}]}, "descriptionModule"=>{"briefSummary"=>"The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to acromegaly.", "detailedDescription"=>"The purpose of this study is to investigate the treatment and natural history of acromegaly. We have a longstanding interest in acromegaly treatment, and a cohort that has been followed for 30 years, or more in some cases. We will continue to follow patients and recruit new patients for treatment and follow-up."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["ADULT", "OLDER_ADULT"], "minimumAge"=>"18 years", "samplingMethod"=>"NON_PROBABILITY_SAMPLE", "studyPopulation"=>"The study involved patients who were referred to us and had acromegaly.@@@@@@", "healthyVolunteers"=>false, "eligibilityCriteria"=>"* INCLUSION CRITERIA:\n\nPatients will be enrolled who are 18 years of age or over who are referred for care."}, "identificationModule"=>{"nctId"=>"NCT00001981", "briefTitle"=>"The Treatment and Natural History of Acromegaly", "organization"=>{"class"=>"NIH", "fullName"=>"National Institutes of Health Clinical Center (CC)"}, "officialTitle"=>"Acromegaly Treatment and Natural History", "orgStudyIdInfo"=>{"id"=>"850082"}, "secondaryIdInfos"=>[{"id"=>"85-DK-0082"}]}, "armsInterventionsModule"=>{"armGroups"=>[{"label"=>"Patients with acromegaly", "description"=>"Patients with acromegaly"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"20892", "city"=>"Bethesda", "state"=>"Maryland", "country"=>"United States", "facility"=>"National Institutes of Health Clinical Center, 9000 Rockville Pike", "geoPoint"=>{"lat"=>38.98067, "lon"=>-77.10026}}], "overallOfficials"=>[{"name"=>"Phillip Gorden, M.D.", "role"=>"PRINCIPAL_INVESTIGATOR", "affiliation"=>"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)"}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "class"=>"NIH"}, "responsibleParty"=>{"type"=>"SPONSOR"}}}}
