Cleft Palate Surgery and Speech Development
Launched by UNIVERSITY OF FLORIDA · Sep 17, 1999
Trial Information
Current as of July 04, 2025
Completed
Keywords
ClinConnect Summary
This study is conducted with patients with complete unilateral cleft lip and palate. The subjects will have their palatal clefts surgically repaired by either the von Langenbeck or the Furlow double z-plasty palatoplasty. Patients will be randomly assigned to four groups, to have with the von Langenbeck palatoplasty with intravelar veloplasty or the Furlow double opposing z-plasty palatoplasty between 9 and 12 months of age or between 15 and 18 months of age. Lip repair will be randomized to either the Spina or Millard method and will be accomplished by six months prior to palatoplasty. The...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Unrepaired unilateral cleft lip and palate
- • Lip repair surgery to be accomplished by 3-6 months of age
- • Able to return to research site at least once a year for follow-up
- Exclusion Criteria:
- • Patients with concomitant conditions (ie. mental retardation, deafness)
- • Patients with Simonart Band of the cleft
- • Patients who could not return to research site on a yearly basis
About University Of Florida
The University of Florida, a leading research institution, is dedicated to advancing healthcare through innovative clinical trials. With a focus on enhancing patient outcomes and exploring new therapeutic avenues, the university leverages its extensive resources, interdisciplinary expertise, and state-of-the-art facilities to conduct rigorous research across a variety of medical fields. Committed to ethical standards and patient safety, the University of Florida fosters collaboration among researchers, healthcare professionals, and community stakeholders to translate scientific discoveries into impactful clinical applications.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Gainesville, Florida, United States
Bauru, Sao Paulo, Brazil
Patients applied
Trial Officials
William N Williams, Ph.D
Principal Investigator
Univerisity of Florida
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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