ClinConnect ClinConnect Logo
Search / Trial NCT00047996

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Launched by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) · Oct 22, 2002

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Dna Endothelial Function Leukocyte Gene Expression Rna Natural History Sickle Cell Coronary Artery Disease Cad Healthy Volunteer Hv

ClinConnect Summary

This clinical trial is studying how blood samples from people with sickle cell disease and healthy volunteers can help researchers understand diseases related to blood vessels better. By collecting these samples, scientists hope to develop new tests that can improve treatment and care for patients with sickle cell disease and other similar conditions.

To participate in this study, you need to be at least 18 years old, and both men and women are welcome. If you have sickle cell disease or other chronic blood conditions, there are specific hemoglobin levels that will determine if you can donate blood. However, if you want to donate saliva or urine, there are no restrictions based on hemoglobin levels. If you join the study, you can expect to provide a blood sample, among other things, to help advance important research. The trial is currently recruiting participants, so if you’re interested, this could be a great opportunity to contribute to medical research.

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • Males or females of age 18 years and older can be included in the study.
  • EXCLUSION CRITERIA:
  • Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men.
  • Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL.
  • A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility.
  • There are no exclusion criteria for participants donating saliva or urine.

About National Heart, Lung, And Blood Institute (Nhlbi)

The National Heart, Lung, and Blood Institute (NHLBI) is a leading component of the National Institutes of Health (NIH), dedicated to advancing research and clinical trials focused on cardiovascular, pulmonary, and hematologic diseases. With a mission to improve public health through innovative research, the NHLBI supports a wide range of studies aimed at understanding, preventing, and treating heart and lung conditions. By collaborating with academic institutions, healthcare providers, and patient communities, the NHLBI strives to translate scientific discoveries into effective clinical practices, ultimately enhancing the quality of life for individuals affected by these critical health issues.

Locations

Bethesda, Maryland, United States

Fairfax, Virginia, United States

Patients applied

JC

2 patients applied

Trial Officials

Swee Lay Thein, M.D.

Principal Investigator

National Heart, Lung, and Blood Institute (NHLBI)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials