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Search / Trial NCT00064870

Alzheimer's Disease Genetics Study

Launched by INDIANA UNIVERSITY · Jul 15, 2003

Trial Information

Current as of August 21, 2025

Recruiting

Keywords

Alzheimer Disease Late Onset Alzheimer Disease Risk Factor Genes Genetics Initiative Dementia

ClinConnect Summary

The Alzheimer's Disease Genetics Study is looking into the genes that may cause Alzheimer's Disease (AD), particularly in families where multiple members have been diagnosed with AD or dementia. The goal is to better understand the genetic factors that contribute to these conditions. If you have two living family members with a diagnosis of AD or another form of dementia, and you have access to certain biological samples like fresh blood or frozen brain tissue, you may be eligible to participate in this important research.

Participants will help researchers by providing genetic material, but it's important to know that this study does not offer personal genetic counseling, and individual test results won't be shared with participants or their families. The study is currently recruiting individuals of all ages and genders, as long as they meet the eligibility criteria. This research could pave the way for better understanding and treatment of Alzheimer's Disease in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Two living family members diagnosed with AD or other dementia with any age of onset
  • Biological samples available
  • Fresh blood, or
  • Immortalized lymphoblastic cell lines, or
  • 3-5 grams of frozen cerebral cortex; fixed samples are not accepted
  • Please note: this study does not include genetic counseling; because no personal identifying information such as name or date of birth is attached to samples, results of individual tests are not available to participants or family members.
  • Exclusion Criteria:
  • Does not meet inclusion criteria
  • Member of a family that was included in the National Institute of Mental Health AD Genetics Sib Pair collection

About Indiana University

Indiana University, a leading research institution, is committed to advancing healthcare through innovative clinical trials and rigorous scientific inquiry. With a focus on improving patient outcomes, the university conducts a wide range of studies across various medical disciplines, leveraging its extensive resources and collaborative networks. Indiana University's dedication to ethical research practices and community engagement ensures that its clinical trials not only contribute to scientific knowledge but also prioritize participant safety and well-being. Through its commitment to excellence, Indiana University plays a pivotal role in shaping the future of medicine and enhancing public health.

Locations

Multiple Locations, Indiana, United States

Patients applied

0 patients applied

Trial Officials

Tatiana M. Foroud, PhD

Principal Investigator

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD), Indiana University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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