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Search / Trial NCT00077909

Study of Lung Proteins in Patients With Pneumonia

Launched by NATIONAL INSTITUTES OF HEALTH CLINICAL CENTER (CC) · Feb 12, 2004

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Proteomics Infection Pneumonia Mass Spectrometry Bal Natural History Lung Pulmonary Disease Lung Infiltrates

ClinConnect Summary

This clinical trial is studying the different proteins found in the lungs of patients with pneumonia. Pneumonia is an illness that causes inflammation in the lungs, often due to an infection, and can be diagnosed through chest X-rays and physical exams. However, these methods do not reveal what specifically causes the inflammation. By examining lung proteins, researchers hope to identify which proteins are linked to certain types of pneumonia. This could help in developing better treatments for the disease.

To participate in the study, patients must be undergoing a procedure called bronchoscopy, which involves using a thin tube to look at the lungs, and a rinse of the airways to collect fluid for testing. Participants will also provide a small blood sample for comparison. The study is open to individuals aged 3 to 100 years old, and consent can be given by a parent or guardian for younger participants. If you are interested in this study or have questions, please talk to your healthcare provider for more information.

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • All eligible patients undergoing diagnostic bronchoscopy who provide consent for proteomic analysis of BAL fluid supernatant and chart review of patient characteristics will be included in this study.
  • A parent/guardian may provide consent for a child age 17 or under and a Legally Authorized Representative (LAR) may provide consent for adults unable to consent.
  • EXCLUSION CRITERIA:
  • Patients undergoing bronchoscopy but not wanting to participate with either the chart review or the proteomic analysis of BAL fluid supernatant will be excluded.

About National Institutes Of Health Clinical Center (Cc)

The National Institutes of Health Clinical Center (CC) is the nation's largest hospital dedicated exclusively to clinical research, serving as a pivotal facility for advancing medical knowledge and innovative therapies. Located in Bethesda, Maryland, the Clinical Center provides a unique environment where patients have access to cutting-edge treatments and participate in groundbreaking clinical trials across a wide range of diseases. As a leader in translational research, the CC integrates patient care with scientific investigation, fostering collaboration among researchers, clinicians, and patients to accelerate the development of new interventions and improve health outcomes.

Locations

Bethesda, Maryland, United States

Bethesda, Maryland, United States

Patients applied

JT

1 patients applied

Trial Officials

Anthony F Suffredini, M.D.

Principal Investigator

National Institutes of Health Clinical Center (CC)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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