Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

Launched by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) · Mar 31, 2005

Keywords

ClinConnect Summary

This clinical trial is focused on the long-term evaluation and follow-up care of patients who have received stem cell transplants from a donor. The study aims to monitor how well these patients respond to their treatment, check for any signs of their disease returning, and identify any long-term effects related to the transplant. It is open to patients aged 10 to 80 who had their first stem cell transplant at least three years ago at the NIH Clinical Center.

If you participate in this trial, you will visit the clinic once a year for various check-ups. These may include physical exams, blood and urine tests, and procedures like bone marrow biopsies to check the health of your blood cells. You may also undergo imaging tests to see how your organs are functioning and lung and heart tests to evaluate your overall health. Depending on your condition, if any issues arise, you might receive standard treatments or be offered new experimental therapies. This study is important as it helps doctors understand the long-term impact of stem cell transplants and improve care for future patients.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA-TRANSPLANT RECIPIENTS:
• • Patients surviving three years or more from date of first stem cell transplant who have been treated.
• • -With an experimental allogeneic stem cell transplant on a NHLBI HB protocol
• • Or
• • -With a standard of care allogeneic stem cell transplant on an NHLBI protocol
• • Or
• • -Selectively, when the allogenic transplant was conducted outside the NIH, but the subject has a special condition of interest to the research team
• • Age greater than or equal to 7 years old and age less than or equal to 80
• • For adults: Ability to comprehend the investigational nature of the study and provide informed consent. For minors: Written informed consent from one parent or guardian and informed assent: The process will be explained to the minor on a level of complexity appropriate for their age and ability to comprehend.
• EXCLUSION CRITERIA-STEM CELL TRANSPLANT RECIPIENTS:
• • None, all patients meeting the inclusion criteria will be eligible