Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies

Launched by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID) · Jun 15, 2005

Keywords

ClinConnect Summary

This clinical trial is focused on collecting blood plasma and white blood cells from healthy volunteers and patients with HIV using a procedure called apheresis. Apheresis is a safe method that allows healthcare providers to gather specific components of your blood through a simple blood draw. The collected blood samples will be used for important laboratory research to help us understand HIV and the immune system better.

To participate, you need to be at least 18 years old and have good access to veins for blood draws. You should also meet certain health criteria, such as having normal blood pressure and adequate blood counts. During the procedure, you'll either have your blood processed through a special machine that separates the plasma and white cells or have a pint of blood drawn like a standard blood donation. It's important to know that the collected blood may also be tested for various viral infections and stored for future research. If you're interested in helping advance medical research and meet the eligibility criteria, this could be a great opportunity for you!

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• • 18 years of age or older
• • Adequate venous access
• • Blood pressure less than or equal to 180/100; pulse rate 50-100, unless a lower pulse rate is considered normal for the volunteer (e.g. a conditioned athlete)
• • Adequate blood counts if undergoing apheresis (HIV positive volunteers and volunteers with vasculitis or other inflammatory diseases: hemoglobin greater than or equal to 9.0 g/dL, HCT greater than or equal to 28%, platelets greater than or equal to 50,000; HIV negative volunteers: hemoglobin greater than or equal to 12.5 g/dL, HCT greater than or equal to 38%, platelets greater than or equal to 150,000)
• • Willing and able to provide written informed consent, comply with study requirements and procedures, and comply with clinic policies (including stored samples, hepatitis screening, and genetic testing including HLA testing)
• EXCLUSION CRITERIA:
• • Pregnant and/or breast-feeding women
• • Currently abusing alcohol or other drugs
• • Any medical condition for which the PI feels apheresis or other sample collection procedures might be contraindicated