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Search / Trial NCT00178516

Vitamin E and Male Infertility

Launched by UNIVERSITY OF ROCHESTER · Sep 13, 2005

Trial Information

Current as of June 26, 2025

Completed

Keywords

Male Infertility

ClinConnect Summary

Sperm DNA damage is an emerging cause of male infertility that is likely to be more common among men with increased reactive oxygen species in the ejaculate. Vitamin E can protect the sperm membrane from oxidative damage and increased levels are associated with low levels of reactive oxygen species. This is a study of Vitamin E levels in the spermatozoa and sera of 48 infertile men, and 20 fertile men as a control group, to look for correlations between sperm vitamin E levels and the degree of sperm DNA fragmentation. Dietary intake of antioxidants will also be included.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • infertile men with previously abnormal semen analyses.
  • Control group: fertile adult males
  • Exclusion Criteria:
  • Proxceed use within 3 months of the start of study.
  • Vitamin E supplements with \> 45 IU daily

About University Of Rochester

The University of Rochester is a leading academic institution dedicated to advancing medical research and improving patient care through innovative clinical trials. Renowned for its commitment to excellence in education, research, and clinical practice, the university fosters a collaborative environment that integrates cutting-edge scientific inquiry with practical applications in healthcare. With a focus on diverse therapeutic areas, the University of Rochester aims to enhance treatment options and outcomes for patients while contributing to the broader scientific community through rigorous study design and ethical standards in clinical research.

Locations

Rochester, New York, United States

Patients applied

0 patients applied

Trial Officials

Vivian Lewis, MD

Principal Investigator

University of Rochester

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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