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Search / Trial NCT00193791

Concomitant Chemoradiation in Advanced Stage Carcinoma Cervix

Launched by TATA MEMORIAL HOSPITAL · Sep 13, 2005

Trial Information

Current as of August 11, 2025

Completed

Keywords

Carcinoma Cervix Figo Stage Iiib Radiation Therapy Chemoradiation Treatment Related Toxicities Cervical Cancer Cervix Cancer

ClinConnect Summary

Carcinoma cervix is the commonest malignancy seen in Asian women and constitutes approximately 30% of all cancers (1). It is also the leading cause of cancer mortality in India. Nearly 50% of the patients present with advanced stages (FIGO Stage III/IV). The main stay of treatment has traditionally been radical radiation therapy and over decades the survival rates have achieved a plateau of 30 - 45% at 5 years. In developing countries the socioeconomic problems, illiteracy, late presentation and irregular follow-up have further compromised our survivals. Over the last decade there have been...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Histologically proven squamous carcinoma of cervix
  • Performance index world health organization (WHO) grade 0 or 1
  • Patients below 65 years of age
  • FIGO Stage IIIB
  • Normal ECG and Cardiovascular system
  • Normal hematological parameters
  • Normal renal and liver function tests
  • Exclusion Criteria:
  • Co-morbid conditions like medical renal disease
  • Medical or Psychological condition that would preclude treatment
  • H/o Previous treatment / Pregnancy
  • Patient unreliable for treatment completion and follow-up.

About Tata Memorial Hospital

Tata Memorial Hospital (TMH) is a premier cancer treatment and research institution located in Mumbai, India, dedicated to providing comprehensive cancer care, conducting advanced research, and offering education in oncology. Established in 1941, TMH is recognized for its commitment to improving cancer treatment outcomes through innovative clinical trials and translational research. The hospital plays a pivotal role in the development of new therapies and treatment protocols, collaborating with national and international research organizations to enhance the understanding of cancer biology and improve patient care. With a multidisciplinary team of experts, TMH strives to foster a compassionate environment that prioritizes patient welfare while advancing scientific knowledge in the field of oncology.

Locations

Mumbai, Maharashtra, India

Patients applied

0 patients applied

Trial Officials

Shyamkishore J Shrivastava, MD,DNB(RT)

Principal Investigator

Professor & Head, Department of Radiation Oncology, Tata Memorial Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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