Non Invasive Ventilation and Weaning : VENISE Trial

Launched by UNIVERSITY HOSPITAL, ROUEN · Sep 13, 2005

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • endotracheal mechanical ventilation for 48 hours or more for acute respiratory failure in chronic respiratory failure patients (obstructive or restrictive disease),
• • patient ready to be weaned (steady respiratory and hemodynamic conditions for 24 hours),
• • spontaneous breathing trial failure occurring between 5 minutes and 2 hours, judged on clinical and/or arterial blood gas tolerance,
• • written informed consent obtained (patient or family)
• Exclusion Criteria:
• • respiratory and hemodynamic instability
• • initial intubation considered as difficult
• • swallowing disorders suspected
• • inefficient cough
• • bronchial hypersecretion at the weaning time
• • non cooperant patient
• • contra-indications for nasal or facial mask (facial skin lesions,...)
• • recent history of upper gastro-intestinal surgery
• • recent history of myocardial infarction