Fish Oil Supplementation in Lactation

Launched by UNIVERSITY OF COPENHAGEN · Dec 15, 2005

Keywords

ClinConnect Summary

Background:

Studies indicate that infants, who are fed formula without n-3 LCPUFA, have slower visual development than those, who receive n-3 LCPUFA in breast-milk. The mental development seems also to depend on whether infants are breast-fed or not. Long-term health has also been proposed to be affected (The infant origin of adult disease hypothesis). It is not clear whether these differences is due to dietary LCPUFA as comparison of breast-fed and formula-fed infants are complicated by the socio-demographic differences that exist between mother, who choose to breast-feed or not. Recent s...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant women with uncomplicated singleton pregnancy
• • No metabolic disorders and prepregnancy BMI \< 30 kg/m2
• • Intention to exclusively breast-feed for 4 mo
• • Fish intake below the Danish mean or above 80th percentile (reference group)
• Exclusion Criteria:
• • Pre- or post term delivery (\< 37 or \> 43 wks of gestation)
• • Abnormal weight for gestation (outside 10th-90th percentile range)
• • Apgar score 5 min after delivery \< 8
• • Infant admission to a neonatal department
• • If supplementation did not begin within 2 wks after delivery