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Search / Trial NCT00284024

Effectiveness of Domperidone to Increase Breastmilk Supply in Mothers With Low Supply

Launched by HAMILTON HEALTH SCIENCES CORPORATION · Jan 27, 2006

Trial Information

Current as of June 04, 2025

Terminated

Keywords

Breastfeeding Domperidone Efficacy Randomized Controlled Trial Compliance

ClinConnect Summary

Breastfeeding alone, until an infant is 6 months of age, is the best form of infant nutrition. There are many ways to help women breastfeed when they are having difficulties with the process, mostly involving support from a lactation consultant. However, some women, despite all appropriate non-medical interventions and support do not produce sufficient breast milk to meet the nutritional needs of their infant.

This is a feasibility study to determine how domperidone affects breast milk production in women with insufficient milk supply feeding term infants. This project will serve to refine...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Women
  • healthy women
  • inadequate milk supply
  • read/speak English
  • Infants
  • healthy term infants (≥ 38 weeks gestational age)
  • age ≥ 2wks and ≤3mths
  • surpassed birth weight
  • Exclusion Criteria:
  • Mother
  • cardiac anomalies
  • breast or endocrine abnormalities (i.e. breast CA, pituitary adenomas)
  • medications contraindicated with domperidone use
  • drug or alcohol use
  • use of hormonal contraception
  • Infant
  • physical anomalies making breastfeeding difficult (i.e. cleft palate)
  • cardiac anomalies

About Hamilton Health Sciences Corporation

Hamilton Health Sciences Corporation is a leading healthcare provider in Canada, renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a focus on translating scientific discoveries into effective treatments, the organization operates a network of hospitals and specialized centers that facilitate cutting-edge research across various medical disciplines. Hamilton Health Sciences is dedicated to fostering collaboration among researchers, healthcare professionals, and industry partners, ensuring that clinical trials are conducted with the highest ethical standards and rigor. Through its robust research infrastructure, the corporation aims to enhance health outcomes and contribute to the global body of medical knowledge.

Locations

Hamilton, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Katalin Ivanyi, MD

Principal Investigator

McMaster University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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