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Search / Trial NCT00305305

Brain Development Research Program

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Mar 17, 2006

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Agenesis Corpus Callosum Polymicrogyria Dandy Walker Brain Malformation Autism Epilepsy Mental Retardation Mri Agenesis Of The Corpus Callosum (Complete Or Partial) Confirmed By A Brain Mri. Aicardi Syndrome.

ClinConnect Summary

The Brain Development Research Program at the University of California, San Francisco (UCSF) is studying the genetic causes of certain brain disorders, specifically those that affect how the brain develops. This includes conditions like Aicardi syndrome, polymicrogyria, and Dandy-Walker malformation, which can lead to challenges with thinking and seizures. The researchers aim to learn more about these genetic factors so they can create better treatments for patients with these conditions.

If you or your child has been diagnosed with agenesis or dysgenesis of the corpus callosum (which means the brain's communication pathway is not fully formed or developed), polymicrogyria, or Dandy-Walker malformation, you may be eligible to participate in this study. An MRI scan of the brain is needed to confirm the diagnosis. This study is currently looking for participants of all ages and genders. Those who join can expect to contribute to important research that could help improve the understanding and treatment of these brain disorders.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of agenesis or dysgenesis of the corpus callosum, polymicrogyria, or Dandy-Walker malformation
  • Should be confirmed by an MRI (Magnetic Resonance Imaging) of the brain
  • Exclusion Criteria:
  • Fully formed but hypoplastic corpus callosum

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

San Francisco, California, United States

Patients applied

0 patients applied

Trial Officials

Elliott H Sherr, MD, PhD

Principal Investigator

University of California, San Francisco

James Barkovich, MD

Principal Investigator

University of California, San Francisco

Pratik Mukherjee, MD, PhD

Principal Investigator

University of California, San Francisco

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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