Prophylaxis With Caspofungin in High-Risk Liver Transplantation

Launched by GRUPO DE ESTUDIO DE INFECCIONES EN TRANSPLANTADOS · Jun 4, 2006

Keywords

ClinConnect Summary

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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or older
• • Patient has received an orthotopic liver transplantation
• • Patient meets criteria, as defined per protocol, for being considered at high risk of developing an invasive fungal infection post-liver transplantation
• • For women of childbearing potential, patient must have a negative serum or urine pregnancy test
• Exclusion Criteria:
• • Any systemic antifungal therapy (other than fluconazole for a maximum of 7 days) within 14 days of the administration of the study drug.
• • Documented (proven/probable) or suspected (possible) invasive fungal infection at the time of enrollment.
• • Abnormal laboratory values as defined per protocol.
• • Allergy, hypersensitivity, or any serious reaction to an echinocandin antifungal.
• • Patient not expected to survive at least 5 days.
• • Patient is pregnant or breast feeding.