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Nutrition Intervention Trials in Linxian Follow-up Study

Launched by NATIONAL CANCER INSTITUTE (NCI) · Jun 19, 2006

Trial Information

Current as of October 03, 2025

Enrolling by invitation

Keywords

Epidemiology Cancer Environment Genetics Nutrition Natural History

ClinConnect Summary

This is a long‑term follow‑up study of about 34,000 adults who took part in two large nutrition trials in Linxian, China (1985–1991) that looked at vitamins and minerals to help prevent esophageal and stomach cancers. The follow‑up is observational, meaning researchers will watch what happens over time to see cancer rates and overall deaths after the original trials ended, and to explore how nutrition, genetics, and the environment might relate to cancer and stroke. It’s not testing a new treatment, just gathering information to learn more from people who were in the earlier studies.

If you were part of the original Linxian trials, you may be invited to participate in this follow‑up. Eligible adults are 18 to 100 years old; the study uses non‑random, invitation‑based enrollment. The National Cancer Institute leads the project. Participants might be asked to complete interviews, nutrition surveys, and provide a blood sample for genetic and environmental research related to cancer and stroke. Again, no new medicine or device is being studied. The study is ongoing, with participation and data collection continuing toward an estimated completion in 2026.

Gender

ALL

Eligibility criteria

  • No eligibility criteria listed.

About National Cancer Institute (Nci)

The National Cancer Institute (NCI) is a prominent component of the National Institutes of Health (NIH), dedicated to advancing cancer research and improving patient outcomes through innovative clinical trials. As a leading sponsor of cancer-related studies, NCI focuses on facilitating the development of new therapies, enhancing prevention strategies, and understanding the biology of cancer. The institute collaborates with academic institutions, healthcare providers, and industry partners to conduct rigorous clinical trials that aim to translate scientific discoveries into effective treatments. NCI’s commitment to fostering a robust research environment supports the mission to eliminate cancer as a major health problem.

Locations

Beijing, China

Patients applied

0 patients applied

Trial Officials

Christian C Abnet, Ph.D.

Principal Investigator

National Cancer Institute (NCI)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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