Biliary Atresia Study in Infants and Children

Launched by ARBOR RESEARCH COLLABORATIVE FOR HEALTH · Jun 27, 2006

Keywords

ClinConnect Summary

The Biliary Atresia Study in Infants and Children is a clinical trial aimed at understanding biliary atresia, a serious liver condition affecting young children. Researchers want to learn more about what causes this disease and how it progresses over time. To do this, they will collect medical information, genetic material, and samples from participants. The study will help identify specific genes that may play a role in the disease and track the health of children with biliary atresia who have not had a liver transplant.

To be eligible for this study, participants must be diagnosed with biliary atresia and be between 6 months and 20 years old. They can either have their original liver or have undergone a liver transplant. Parents or guardians will need to give permission for younger participants, while those 18 and older can consent for themselves. If you join the study, you can expect to attend scheduled visits where your health will be monitored, and you will help researchers gather important information that could lead to better treatments for biliary atresia in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Participants need to have a confirmed diagnosis of BA determined by chart review including review of pertinent diagnostic biopsy reports, radiologic reports and surgical reports (if surgery was performed).
• • 2. Participants need to be \>6 months of age up to and equal to the age of 20 (participants enrolled at 20 years of age will have one visit).
• • 3. Participants either have their native liver or have a confirmed liver transplantation.
• • 4. Parent, guardian or participant (if 18 years of age or older) is willing to provide informed consent and, when appropriate, the participant is willing to assent.
• Exclusion Criteria:
• • 1. Currently participating in the ChiLDReN study PROBE
• • 2. Inability to confirm original diagnostic evaluation of biliary atresia
• • 3. Inability or unwillingness of family or participant to participate in all scheduled visits.