Comparison Between Marijuana Smoked in Cigarette Paper Versus Cigar Paper

Launched by NEW YORK STATE PSYCHIATRIC INSTITUTE · Sep 7, 2006

Keywords

ClinConnect Summary

There has been a rapid increase in marijuana use during the 1990s, with the most recent generation often smoking marijuana in the form of 'blunts' as opposed to more traditional routes such as in pipes or in cigarette paper. A blunt is made by removing the tobacco from a cigar and replacing it with marijuana (Golub and Johnson, 1999). The cigar wrapper contains tobacco and nicotine, which may interact with the cardiovascular and subjective effects of the marijuana to produce a different set of effects and risks than cigarette paper. Anecdotally, marijuana smokers report that blunts are more...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Current blunt marijuana use (minimum of twice/week) drug screen
• • 21-45 years of age
• • Practicing an effective form of birth control (condoms, diaphragm, birth control pill, IUD)
• Exclusion Criteria:
• • Current, repeated illicit drug use(excluding marijuana)
• • Heavy cigarette use (\> 10 cigarettes/day)
• • Presence of significant medical illness (e.g., diabetes, cardiovascular disease, hypertension)
• • Laboratory tests outside normal limits that are clinically unacceptable to the study physician (BP \> 140/90; hematocrit \< 34 for women, \< 36 for men)
• • Significant adverse reaction to marijuana
• • Current parole or probation
• • Pregnancy or current lactation
• • History of significant violent behavior
• • Major current Axis I psychopathology(e.g., mood disorder with functional impairment or suicide risk, anxiety disorder, schizophrenia)
• • History of heart disease
• • Current use of any over-the-counter or prescription