Movicol in Childhood Constipation (ProMotion Study)

Launched by NORGINE · Nov 24, 2006

Keywords

ClinConnect Summary

Patients received Movicol treatment until disimpaction was achieved according to the following regime:

Day 1: Ages 2 - 4 received 1 (one) sachet whilst 5 - 11 year olds received 2 (two).

Day 2: Ages 2 - 4 received 2 (two) sachets whilst 5 - 11 year olds received 3 (three).

Day 3: Ages 2 - 4 received 2 (two) sachets whilst 5 - 11 year olds received 4 (four).

Day 4: Ages 2 - 4 received 3 \*three) sachets whilst 5 - 11 year olds received 5 (five).

Day 5: Ages 2 - 4 received 3 (three) sachets whilst 5 - 11 year olds received 6 (six).

Day 6: Ages 2 - 4 received 4 (four) sachets whilst 5 - ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients that, in the opinion of the investigator, are constipated/fecally impacted as to require hospital stay to treat and/or relieve the impaction
• • children aged 2 - 11 years old inclusive
• • patients of either sex
• Exclusion Criteria:
• • Patients with
• • intestinal perforation or obstruction
• • severe inflammatory conditions of the intestinal tract
• • uncontrolled renal/hepatic/cardiac diseases
• • uncontrolled endocrine disorder(s)
• • any neuromuscular condition affecting bowel function
• • hypersensitivity to lactulose or PEG or other constituent of Movicol
• • patients who have taken any investigational drug in the three months
• • patients or patients whose parents would in the opinion of the investigator are unable to comply with requirements of the study