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Search / Trial NCT00417339

Protein-bound Uremic Retention Solutes and Long Nocturnal Hemodialysis: a Longitudinal Analysis

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Dec 28, 2006

Trial Information

Current as of August 11, 2025

Completed

Keywords

Hemodialysis Dialysis Adequacy Uremic Retention Solute

ClinConnect Summary

Although remarkable progress has been made, chronic kidney disease still poses a major burden on both individual patients, as well as on society as a whole. There is a strong inverse relationship between decreasing renal function, as estimated by glomerular filtration rate, and mortality rate, especially death due to cardiovascular disease. The exact cause(s) remain to be elucidated. Uremic toxins might play an important role.

In the course of decreasing renal function the concentration of numerous intracellular and extracellular compounds vary from the non-uremic state. A still increasing...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Start hemodialysis during 2007
  • Age over 18 years
  • Informed consent
  • Exclusion Criteria:
  • Non consent

About Universitaire Ziekenhuizen Ku Leuven

Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.

Locations

Clayton, Victoria, Australia

Geelong, Victoria, Australia

Leuven, Vlaams Brabant, Belgium

Hasselt, Limburg, Belgium

Patients applied

0 patients applied

Trial Officials

Björn KI Meijers, MD

Principal Investigator

Universitaire Ziekenhuizen KU Leuven

Pieter Evenepoel, MD, PhD

Study Director

Universitaire Ziekenhuizen KU Leuven

Tom Dejagere, MD

Principal Investigator

Virga Jesse Ziekenhuis

Nigel Toussaint, MD

Principal Investigator

Geelong Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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