Minimum Local Anesthetic Volume of Bupivacaine in Labour Epidurals
Launched by SAMUEL LUNENFELD RESEARCH INSTITUTE, MOUNT SINAI HOSPITAL · Mar 19, 2007
Trial Information
Current as of August 11, 2025
Completed
Keywords
ClinConnect Summary
Epidural administration of local anesthetics during labor produces analgesia, sympathetic block and motor block. The characteristics of the block depend on the volume and concentration of the local anesthetic that is used as well as the potential use of adjuncts. Although many researchers have investigated the efficacy of different drugs at different concentrations, the volumes used have been arbitrary. There is limited data regarding the minimum volume that is necessary for a successful anesthetic for a given concentration of bupivacaine.
This study is conducted as a prospective, randomiz...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • ASA I or II
- • Full term (more than 37 weeks gestation)
- • Singleton pregnancy, vertex presentation
- • Regular painful contractions occurring at least every 5 minutes
- • Cervical dilatation \< 5 cm
- Exclusion Criteria:
- • Any contraindication to epidural anesthesia
- • Accidental dural puncture
- • Allergy or hypersensitivity to bupivacaine
- • Women who have received opioids or sedative medications within the last 4 hours
About Samuel Lunenfeld Research Institute, Mount Sinai Hospital
The Samuel Lunenfeld Research Institute at Mount Sinai Hospital is a leading biomedical research facility dedicated to advancing our understanding of human health and disease. Renowned for its innovative research programs, the institute focuses on areas such as cancer, genetics, and reproductive health, fostering collaboration among top-tier scientists and clinicians. With a commitment to translating research findings into clinical applications, the Samuel Lunenfeld Research Institute plays a pivotal role in the development of novel therapies and interventions, thereby contributing to improved patient outcomes and the advancement of medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Toronto, Ontario, Canada
Patients applied
Trial Officials
Jose CA Carvalho, MD PhD
Principal Investigator
MOUNT SINAI HOSPITAL
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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