Analysis of a Beneficial Effect of Prolonges Topical Steroid Treatment After Low-risk Penetrating Keratoplasty
Launched by UNIVERSITY OF ERLANGEN-NÜRNBERG MEDICAL SCHOOL · Mar 20, 2007
Trial Information
Current as of August 02, 2025
Completed
Keywords
ClinConnect Summary
PURPOSE: To assess the impact of duration of topical steroid treatment on the incidence of endothelial graft rejection following normal-risk penetrating keratoplasty (PK). DESIGN: Prospective, institutional, longitudinal, randomized interventional trial including 406 eyes (age: 52 \>= 19 years; follow-up: 42 \>= 18 months). METHODS: Postoperative treatment started with prednisolone acetate 1% eye drops five times daily and was tapered over the first 6 months. Patients were then randomised into either short-term (stop topical steroid treatment) or long-term treatment (continue steroids once ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Low risk keratoplasty
- Exclusion Criteria:
- • High risk keratoplasty
About University Of Erlangen Nürnberg Medical School
The University of Erlangen-Nürnberg Medical School is a prestigious institution dedicated to advancing medical research and improving healthcare outcomes through innovative clinical trials. Renowned for its interdisciplinary approach, the medical school fosters collaboration among experts in various fields, enabling the development of cutting-edge therapies and treatment protocols. With a commitment to ethical standards and patient safety, the institution actively contributes to the global medical community by conducting rigorous clinical studies aimed at enhancing the understanding and management of diverse health conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
friedrich Naumann, MD
Principal Investigator
University of Erlangen-Nürnberg
claus Cursiefen, md
Study Director
University of Erlangen-Nürnberg
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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