No Resistance After Long Term Treatment SERETIDE

Launched by GLAXOSMITHKLINE · Apr 3, 2007

Keywords

ClinConnect Summary

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Gender

ALL

Eligibility criteria

• Inclusion:
• • Positive skin prick test
• • History of asthma (GINA)
• • Regular treatment with FP with/without LABA at least 4 weeks before visit 1
• • History of recurrent episodes of wheezing, breathlessness, chest tightness and/ or coughing in the previous year.
• • Able to use a DISKUS™ inhaler
• • Able perform reproducible lung function tests at Visit 1
• Inclusion criteria treatment period:
• • FEV1 % predicted \> 70%
• • ACT score \< 25 after run-in period
• Exclusion criteria run-in period:
• • Hospitalised for asthma within 4 weeks prior to Visit 1
• • Acute upper respiratory tract infection or a lower respiratory tract infection within 4 weeks prior to Visit 1
• • Oral, parental or depot corticosteroids within 4 weeks prior to Visit 1
• • Hepatic impairment or other significant disease
• Exclusion criteria treatment period:
• • Non-compliance (\< 70%)