Evaluation of a Multispectral Vision Enhancement System for Assessment of Oral Mucosal Lesions

Launched by M.D. ANDERSON CANCER CENTER · Jul 16, 2007

Keywords

ClinConnect Summary

All tissue and cells are made of tiny particles that give off small amounts of light. This light is called fluorescence. Scientists have learned that cancerous cells and normal cells give off different amounts and different types of fluorescence. Scientists need to better understand whether fluorescence from the oral cavity (mouth) can be used to tell which cells are abnormal. This information can help doctors detect pre-cancers.

In order to better understand fluorescence, researchers at the Optical Spectroscopy and Imaging Lab, Department of Bioengineering, Rice University have developed ...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. Subjects with lesions of the oral cavity mucosa or suspicious for malignancy or premalignancy.
• • 2. Subjects with the ability and willingness to sign an informed consent and authorization.
• • 3. Subjects who develop new lesions or alterations in long-standing lesions are eligible, but not required, for re-examination with informed consent.
• Exclusion Criteria:
• • 1. Persons who are medically unfit to undergo superficial punch biopsies of oral mucosa.
• • 2. Persons under the age of 18.