Psychophysical Studies of Cancer Therapy Pain

Launched by M.D. ANDERSON CANCER CENTER · Aug 10, 2007

Keywords

ClinConnect Summary

**Trial Summary: Psychophysical Studies of Cancer Therapy Pain**

This clinical trial is looking into how cancer treatments can cause pain and how we can better understand it. Researchers want to see if special tests can help us learn more about the nerve pain that some patients experience after receiving cancer therapies like chemotherapy. By taking small skin samples from patients who have pain from these treatments, the study aims to find out if the nerve damage is due to a loss of nerve connections in the skin.

To participate in this trial, individuals must be at least 18 years old and either currently experiencing pain from cancer treatments or about to start chemotherapy without having pain yet. Participants will undergo some tests that might cause mild discomfort, but these are designed to help researchers gather important information. This study is open to all genders, and it is currently recruiting participants. If you're interested or think you might qualify, it’s a good idea to discuss it with your healthcare provider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Since moderate pain, albeit brief, will be induced, this feasibility project will be limited to consenting adults, 18 years old or older, in which there is also a well established QST database.
• • 2. The subjects must be able to understand the nature of the study and have signed consent.
• • 3. The patients must either: a) have pain that has developed as a consequence of cancer therapy with either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds or ionizing irradiation. OR b) have no pain that has developed as a consequence of cancer therapy, and are just entering chemotherapy with taxanes, vinka alkaloids, bortezomib, thalidomide, or platinum-based compounds
• • 4. (For Healthy Controls) Willing to participate and have signed an informed consent.
• Exclusion Criteria:
• • 1. Patients who refuse to participate or who are determined incapable of completing the research.
• • 2. (For Healthy Controls) Receiving anti-coagulants, immunosuppressed or diabetic.