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Search / Trial NCT00537004

Language in Primary Progressive Aphasia

Launched by NORTHWESTERN UNIVERSITY · Sep 26, 2007

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Primary Progressive Aphasia Frontotemporal Dementia Semantic Dementia Progressive Nonfluent Aphasia Progressive Aphasia Frontotemporal Lobar Degeneration

ClinConnect Summary

This clinical trial, titled "Language in Primary Progressive Aphasia," aims to better understand how language and brain function change in people diagnosed with primary progressive aphasia (PPA). PPA is a condition that affects a person's ability to speak and understand language over time. Researchers are looking for participants who are right-handed, native English speakers, and can see and hear well enough to follow conversations. To take part, individuals must be able to safely undergo an MRI scan, which is a type of imaging test that helps doctors see inside the brain.

If you or a loved one is interested in participating, you should know that the study is currently recruiting participants. The trial is open to all genders, and it specifically excludes anyone who is left-handed, has a fear of enclosed spaces (claustrophobia), or has other serious health issues that might affect their ability to continue in the study. Participants can expect to contribute to important research that could help improve understanding of PPA and potentially lead to better treatments in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of primary progressive aphasia
  • Right-handed
  • Native English speaker
  • Visual acuity of 20/30 corrected
  • Adequate hearing to follow conversation
  • Safe for an MRI scan
  • Exclusion Criteria:
  • Left-handedness
  • Claustrophobia
  • Presence of significant medical illness that initially or in the future could interfere with continued participation in the study

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Marsel Mesulam, MD

Principal Investigator

Northwestern University Feinberg School of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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