Blood Sampling for Research Related to Sickle Cell Disease

Launched by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) · Oct 10, 2007

Keywords

ClinConnect Summary

This clinical trial is focused on studying sickle cell disease, a condition that affects how red blood cells work and limits their ability to carry oxygen in the body. Researchers want to collect blood samples from both healthy individuals and those with specific blood features related to sickle cell disease. The goal is to gather these samples to help develop new treatments and improve understanding of this disease.

To participate, volunteers need to be at least 18 years old and may include those with sickle cell trait, those with certain blood disorders, or healthy individuals for comparison. During the study, participants will visit the National Institutes of Health Clinical Center, where they will donate a small amount of blood—about 2 teaspoons. There may also be opportunities for participants with unique blood features to donate additional samples later. It's important to note that people who have certain infections, like HIV or Hepatitis, will not be eligible for this study for safety reasons. If you or someone you know might be interested, this could be a valuable opportunity to contribute to sickle cell research.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• • Patients with sickle cell trait
• • Patients with known hemoglobinopathies involving one or two genes for sickle hemoglobin
• • Healthy volunteers for control experiments
• • Age range: adults greater than or equal to 18 years of age
• EXCLUSION CRITERIA:
• • Subjects who are unable to comprehend the investigational nature of the laboratory research are ineligible to enroll in this protocol.
• • As a safety precaution in handling the blood samples, patients with HIV, Hepatitis B or Hepatitis C will be excluded from the study. HIV, Hepatitis B or Hepatitits C testing will not be done under this study. Participants must be co-enrolled under another NIH protocol where the screening evaluation has been performed.