Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty

Launched by GENERAL AND TEACHING HOSPITAL CELJE · Oct 22, 2007

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called pamidronate, which is applied directly to the bone, to see if it can help prevent bone loss after a total hip replacement surgery. The goal is to find out if using pamidronate can reduce the amount of bone loss around the new hip joint compared to a group of patients who will not receive the medication (this group is called the placebo group). Researchers will measure bone density at different times after surgery to see how well the treatment works.

To participate in the trial, patients must be scheduled for a total hip replacement due to hip arthritis. However, women who are pregnant or those who already have a hip implant on the opposite side cannot join. Participants will undergo several tests, including special X-rays, at different points after their surgery to track their bone health. It's important to note that the trial is not yet recruiting participants, so those interested will need to wait for the study to start.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients with hip arthritis scheduled for total cemented hip arthroplasty
• Exclusion Criteria:
• • pregnancy
• • endoprosthesis on contralateral hip