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Search / Trial NCT00556530

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

Launched by ALBERT EINSTEIN COLLEGE OF MEDICINE · Nov 8, 2007

Trial Information

Current as of May 14, 2025

Recruiting

Keywords

Congenital Heart Defects Single Nucleotide Polymorphisms Copy Number Variations Whole Genome Association Study

ClinConnect Summary

This clinical trial is focused on understanding how genetic differences can influence the severity of 22q11.2 deletion syndrome, also known as DiGeorge Syndrome. This is a genetic condition that can lead to issues such as heart problems, unique facial features, and challenges in learning and development. The researchers are looking at DNA samples from individuals with this syndrome to identify specific genetic factors that may make the condition more or less severe for different people.

If you or a loved one has been diagnosed with a 22q11 deletion of at least 3 megabases (Mb), you might be eligible to participate in this study. Unfortunately, those with a smaller deletion or no deletion will not be included. Participants in this trial will help researchers gather important information that could lead to better understanding and treatment options for 22q11.2 deletion syndrome. The trial is currently recruiting, and individuals of all ages and genders are welcome to join. Your involvement could play a crucial role in advancing medical knowledge about this condition.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Has 22q11 deletion of 3 megabases (Mb)
  • Exclusion Criteria:
  • Has 22q11 deletion smaller than 3 Mb or no deletion

About Albert Einstein College Of Medicine

Albert Einstein College of Medicine is a leading academic institution dedicated to advancing biomedical research and medical education. Situated in the Bronx, New York, it is renowned for its commitment to innovative research and training the next generation of physicians and scientists. The college actively engages in a wide range of clinical trials, focusing on translating scientific discoveries into effective therapies and improving patient care. With a collaborative approach that involves multidisciplinary teams, Albert Einstein College of Medicine aims to address significant health challenges and contribute to the global medical community through rigorous research and evidence-based practices.

Locations

Philadelphia, Pennsylvania, United States

New York, New York, United States

Patients applied

0 patients applied

Trial Officials

Bernice E. Morrow, PhD

Principal Investigator

Albert Einstein College of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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