Evaluation of the COGNISION(TM) System as an Event-related Potential (ERP) Collection System.

Launched by NEURONETRIX, INC. · Dec 27, 2007

Keywords

ClinConnect Summary

Patients who have a current diagnosis of mild-moderate dementia and suspected of having Alzheimer's disease (AD) along with cognitively normal age-matched controls will be recruited for this study. The Alzheimer's subjects either will have had a complete clinical and neuropsychiatric workup or will have those tests performed during the study.

Both groups, AD and controls will be asked to listen to a series of sounds and press a button on a handheld control box when a target sound is heard. The COGNISION(TM) headset on each subject's head will then record the electrical signals during this ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria for AD:
• • Age 60 to 85
• • Mild to moderate diagnosis of Alzhiemer's disease
• Inclusion Criteria for Control:
• • Age 60 to 85
• • Cognitively healthy with no complaints
• Exclusion Criteria:
• • Subjects with advanced AD and severe impairment (CDR \> 2, MMSE less than 15)
• • Neurological disorders such as stroke, Parkinson's disease, Huntington's disease, multiple sclerosis, brain tumor, delirium, or psychiatric disorder other than depression (e.g. schizophrenia)
• • Subjects with life threatening illnesses and subjects with significant hearing or visual impairments
• • Subjects with a current prescription for psychoactive pharmaceuticals