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Search / Trial NCT00633451

Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome

Launched by PROAXIS THERAPY · Mar 4, 2008

Trial Information

Current as of June 18, 2025

Completed

Keywords

Shoulder Pain Shoulder Impingement Syndrome Manual Therapy Rehabilitation

ClinConnect Summary

Subacromial impingement syndrome (SAIS) is a frequent cause of shoulder pain. Clinical trials investigating the effectiveness of manual therapy have demonstrated improvements in outcomes when manual therapy has been added to a program of therapeutic exercise. However, the these clinical trials (3) have significant limitations and generalizability. Two of the three 3 trials had a small number of subjects (14 \& 22 subjects) and all 3 trials had only short term follow up (\<12 weeks) and used non-validated self report outcome measures. These limitations reduce the confidence with which clinic...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Symptoms associated with athletic activity (35% of patients)
  • * Diagnosis of shoulder impingement syndrome as evidence by all 3 criteria:
  • 1. Reproduction of symptoms with impingement test: either Hawkins- Kennedy or Neer Test
  • 2. Pain during active shoulder elevation at or above 60 degrees
  • 3. Weakness of rotator cuff or pain during the Empty Can test or during resisted shoulder external rotation
  • Shoulder disability: 25/100 (0 = no disability)
  • Able to understand written and spoken
  • Exclusion Criteria:
  • Severe pain; pain is \> 7/10 on NPRS (0 = no pain)
  • Shoulder surgery on affected shoulder
  • Traumatic shoulder dislocation within the past 3 months
  • Previous rehabilitation for this episode of shoulder pain
  • Reproduction of shoulder pain with active or passive cervical motion
  • Systemic inflammatory joint disease
  • Global loss of passive shoulder ROM, indicative of adhesive capsulitis
  • * Full-thickness rotator cuff tear, as evidenced by any one of the following:
  • 1. Markedly reduced shoulder external rotation strength
  • 2. Drop arm test
  • 3. External rotation lag sign
  • 4. Lift off test
  • 5. Positive findings on MRI or ultrasonography

About Proaxis Therapy

Proaxis Therapy is a leading clinical trial sponsor dedicated to advancing innovative therapeutic solutions through rigorous research and development. With a focus on enhancing patient outcomes, Proaxis Therapy specializes in the design and execution of clinical trials across various therapeutic areas, leveraging cutting-edge methodologies and a commitment to ethical standards. The organization collaborates with healthcare professionals, regulatory bodies, and industry partners to ensure the highest quality of clinical research, ultimately aiming to bring effective treatments to market and improve the quality of life for patients worldwide.

Locations

Greenville, South Carolina, United States

Patients applied

0 patients applied

Trial Officials

Charles A Thigpen, PhD, PT, ATC

Principal Investigator

University of North Florida

Lori A Michener, PhD, PT, ATC

Principal Investigator

Virginia Commonwealth University

Phil McClure, PhD, PT

Principal Investigator

Arcadia University

Angela R Tate, PhD, PT

Study Director

Arcadia University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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