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Search / Trial NCT00680745

Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

Launched by ASTRAZENECA · May 19, 2008

Trial Information

Current as of October 11, 2025

Completed

Keywords

Dapagliflozin Efficacy Safety Sulphonylurea Type 2 Diabetes

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Type 2 Diabetes
  • Treatment with a stable sulphonylurea monotherapy dose that is at least half the maximal recommended dose for a minimum of 8 weeks prior to study
  • Inadequate glycaemic control, defined as A1C ≥ 7.0 % and ≤ 10%
  • Exclusion Criteria:
  • Type 1 Diabetes
  • Hepatic (liver) impairment
  • Renal (kidney) failure or dysfunction

About Astrazeneca

AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.

Locations

Plzen, Czech Republic

Budapest, Hungary

Seoul, Korea, Republic Of

Manila, Philippines

Gdansk, Poland

Zabrze, Poland

Chiang Mai, Thailand

Poznan, Poland

Torun, Poland

Kiev, Ukraine

Bydgoszcz, Poland

Zalaegerszeg, Hungary

Kecskemet, Hungary

Krakow, Poland

Donetsk, Ukraine

Kharkiv, Ukraine

Sopot, Poland

Wroclaw, Poland

Plock, Poland

Chojnice, Poland

Praha 1, Czech Republic

Mosonmagyarovar, Hungary

Siofok, Hungary

Bangkok, Thailand

Eger, Hungary

Szentes, Hungary

Hodonin, Czech Republic

Miskolc, Hungary

Cebu City, Philippines

Balatonfured, Hungary

Marikina City, Philippines

Pasig City, Philippines

Semily, Czech Republic

Zielona Gora, Poland

Ruda Slaska, Poland

Chrzanow, Poland

Elblag, Poland

Zaporozhye, Ukraine

Seongnam, Korea, Republic Of

Czechowice Dziedzice, Poland

Ilawa, Poland

Incheon, Korea, Republic Of

Bekescsaba, Hungary

Wonju, Kangwon Do, Korea, Republic Of

Bucheon, Korea, Republic Of

Csongrad, Hungary

Blansko, Czech Republic

Breclav, Czech Republic

Bruntal, Czech Republic

Ostrava Belsky Les, Czech Republic

Pribram Viii, Czech Republic

Rakovnik, Czech Republic

Gyongyos, Hungary

Mako, Hungary

Tat, Hungary

Jeonju, Chonbuk, Korea, Republic Of

Suwon, Kyunggi Do, Korea, Republic Of

Uljeongbu, Korea, Republic Of

Bielsko Biala, Poland

Ciechocinek, Poland

Gniewkowo, Poland

Grudziadz, Poland

Mragowo, Poland

Zory, Poland

Dnipropetrov'sk, Ukraine

Vinnytsia, Ukraine

Patients applied

0 patients applied

Trial Officials

Krzysztof Strojek, Prof. Dr.

Principal Investigator

Silesian Medical University3-Maja 13/15, 41-800 Zabrze; Poland

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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