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Search / Trial NCT00688727

Cognitive Behavioural Therapy in Dissociative Seizures

Launched by SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST · Jun 2, 2008

Trial Information

Current as of July 02, 2025

Unknown status

Keywords

Non Epileptic Seizures Cognitive Behavioural Therapy Dissociative Disorders Seizure Disorders Randomised Controlled Trial

ClinConnect Summary

Preliminary results from a pilot study demonstrated that cognitive behavioural therapy (CBT) is associated with a significant benefit for patients with dissociative seizures. The current study aims to extend these findings by conducting a randomised controlled trial comparing CBT with standard outpatient medical care. Standard outpatient care has been chosen as the comparison treatment as it most closely resembles what is currently offered to this group of patients by the National Health Service. The primary outcome measure will be seizure frequency. Secondary outcome measures will be work ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • clinical diagnosis of dissociative seizures
  • diagnosis confirmed by video EEG telemetry where practicable
  • aged 16 - 70
  • Exclusion Criteria:
  • co existent diagnosis (past or present) of epilepsy
  • seizure frequency of less than 2 seizures per month
  • current alcohol or drug abuse
  • benzodiazepine use exceeding the equivalent of 10mg diazepam per day.

About South London And Maudsley Nhs Foundation Trust

The South London and Maudsley NHS Foundation Trust (SLaM) is a leading mental health service provider in the UK, renowned for its commitment to delivering high-quality care and advancing mental health research. As a key player in clinical trials, SLaM integrates cutting-edge research with clinical practice, aiming to improve treatment outcomes for patients experiencing a wide range of mental health conditions. The Trust collaborates with academic institutions and healthcare organizations to facilitate innovative studies, contributing to the global understanding of mental health and influencing evidence-based practices. With a focus on patient-centered care, SLaM is dedicated to enhancing the lives of individuals through rigorous scientific inquiry and compassionate support.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Laura Goldstein

Study Director

Institute of Psychiatry

John Mellers

Principal Investigator

Maudsley Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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