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Search / Trial NCT00694512

Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin

Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Jun 6, 2008

Trial Information

Current as of July 06, 2025

Completed

Keywords

ClinConnect Summary

Control subjects will be provided 3 different diets for 2 weeks each. At the end of each diet period participants will be admitted to OHSU Clinical Translation Research Center (CTRC) for blood sampling every 30 minutes for 13.5 hours, to measure levels of hormones. Participants will also have a DXA scan to measure body composition.

PWS subjects will have one admission after eating a standardized diet prepared by caregivers for 2 weeks.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 18 or older.
  • Weight stable for at least 3 months.
  • At lifetime maximal body weight.
  • Exclusion Criteria:
  • Actively losing weight by diet or exercise.
  • Smokers.
  • Alcohol consumption \> 2 drinks per day.
  • Exercise \> 30 minutes 3 times a week.
  • Prescription drug use (except birth control pills, vitamins, or minerals).
  • Type 2 diabetes.
  • Heart disease, cancer, malabsorptive states, or chronic infections that would affect body weight.
  • Weight \> 300 lbs (exceeds the weight limit of the DEXA machine).
  • Hemoglobin \< 12.0 g/dL for women, \< 13.5 g/dL for men

About Oregon Health And Science University

Oregon Health and Science University (OHSU) is a leading academic medical center dedicated to advancing health through research, education, and patient care. As a prominent sponsor of clinical trials, OHSU leverages its extensive expertise in various medical fields to facilitate innovative research aimed at improving patient outcomes. The institution is committed to ethical standards and rigorous scientific methodologies, fostering collaborations that enhance the development of new therapies and interventions. With a focus on translating research discoveries into clinical practice, OHSU plays a pivotal role in shaping the future of healthcare.

Locations

Portland, Oregon, United States

Patients applied

0 patients applied

Trial Officials

Jonathan Q. Purnell, M.D.

Principal Investigator

Oregon Health and Science University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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