Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin
Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Jun 6, 2008
Trial Information
Current as of July 06, 2025
Completed
Keywords
ClinConnect Summary
Control subjects will be provided 3 different diets for 2 weeks each. At the end of each diet period participants will be admitted to OHSU Clinical Translation Research Center (CTRC) for blood sampling every 30 minutes for 13.5 hours, to measure levels of hormones. Participants will also have a DXA scan to measure body composition.
PWS subjects will have one admission after eating a standardized diet prepared by caregivers for 2 weeks.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age 18 or older.
- • Weight stable for at least 3 months.
- • At lifetime maximal body weight.
- Exclusion Criteria:
- • Actively losing weight by diet or exercise.
- • Smokers.
- • Alcohol consumption \> 2 drinks per day.
- • Exercise \> 30 minutes 3 times a week.
- • Prescription drug use (except birth control pills, vitamins, or minerals).
- • Type 2 diabetes.
- • Heart disease, cancer, malabsorptive states, or chronic infections that would affect body weight.
- • Weight \> 300 lbs (exceeds the weight limit of the DEXA machine).
- • Hemoglobin \< 12.0 g/dL for women, \< 13.5 g/dL for men
About Oregon Health And Science University
Oregon Health and Science University (OHSU) is a leading academic medical center dedicated to advancing health through research, education, and patient care. As a prominent sponsor of clinical trials, OHSU leverages its extensive expertise in various medical fields to facilitate innovative research aimed at improving patient outcomes. The institution is committed to ethical standards and rigorous scientific methodologies, fostering collaborations that enhance the development of new therapies and interventions. With a focus on translating research discoveries into clinical practice, OHSU plays a pivotal role in shaping the future of healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Portland, Oregon, United States
Patients applied
Trial Officials
Jonathan Q. Purnell, M.D.
Principal Investigator
Oregon Health and Science University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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