International Pediatric Adrenocortical Tumor Registry

Launched by ST. JUDE CHILDREN'S RESEARCH HOSPITAL · Jun 13, 2008

Keywords

ClinConnect Summary

The International Pediatric Adrenocortical Tumor Registry is a research study aimed at learning more about a rare type of cancer called adrenocortical tumors in children and teenagers. The study will collect important information about the medical history of these young patients, including any family history of cancer. The goal is to understand better how this disease affects patients, what treatments work best, and what the outcomes are. Researchers at St. Jude Children's Research Hospital will also study the tumor cells to investigate the role of specific genes, such as the TP53 gene, which could help explain why these tumors occur.

If your child has been diagnosed with an adrenocortical tumor and is 21 years old or younger, they might be eligible to participate in this study. Additionally, if you are a biological parent of a child with this type of tumor or a relative with a history of cancer and a TP53 mutation, you may also qualify to take part. Participants will provide their medical information and may also contribute biological samples for genetic studies. By participating, you can help researchers gain valuable insights that could improve understanding and treatment for this condition in the future.

Gender

ALL

Eligibility criteria

• STRATIFICATION ASSIGNMENT:
• • Stratum A: participant suspected or confirmed diagnosis of adrenocortical tumor (ACT)
• • Stratum R: relative of participant with ACT and TP53 mutation who has diagnosis of malignancy
• • Stratum P: biological parent of participant with ACT
• Inclusion Criteria - Stratum A (participant with ACT):
• • Age ≤ 21 years old at diagnosis
• • Suspected or confirmed diagnosis of adrenocortical tumor (adenoma, carcinoma or undefined histology).
• • Signed informed consent
• Inclusion Criteria - Stratum R (relative):
• • Any age
• • Diagnosis of malignant tumor
• • Signed informed consent
• Inclusion Criteria - Stratum P (parent):
• • Biological parent of Stratum A participant