Efficiency And Safety Of Association Arbutin, Triamcinolone And Tretinoin In Treatment Of Melasma

Launched by AZIDUS BRASIL · Jul 16, 2008

Keywords

ClinConnect Summary

The melasma is a common hipermelanosis, acquired, symmetrical, with irregular occurring in areas such as photo-exposed face, forehead and temples, can affect the eyelids and tion. The facial regions most affected are: zigomatic (82.4%), parotid (64.7%), front (64.7%), mandible (35.3%) and nasal (35.3%). The injuries of melasma is variable increase of epidermal melanin and inflammatory infiltrate of mild to moderate intensity. Treatment with compounds such as hydroquinone and derivatives, tretinoin, corticosteroids moderate or combination of them all have shown good results, diminishing the ...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women adults aged more than 18 years;
• • Patients suffering from melasma Epidermal the face of mild and moderate;
• • Patients who have not done any treatment for melasma in the 3 months preceding the study;
• • Patients with good mental and physical health;
• • Patients who agree with the purposes of the study and sign the TCLE.
• Exclusion Criteria:
• • Patients with skin diseases other than melasma, which interfere in clinical evaluation as hemangiomas and queloides;
• • Patients with melasma skin or mixed;
• • Patients with sensitivity to agents hipopigmentantes;
• • Patients with sensitivity to fotoprotetores;
• • Patients who are pregnant or breastfeeding;
• • Patients who, at the discretion doctor, are not able to participate in the study;
• • Patients who have carried out any treatment for melasma in the 3 months preceding the study
• • Patients who do not agree with the terms described in the Statement of Informed Consent