Fractional CO2 Treatment of Acne Scars in Asians

Launched by MAHIDOL UNIVERSITY · Sep 5, 2008

Keywords

ClinConnect Summary

* The objective of this study is to investigate the efficacy and side effects of a fractional CO2 laser for treatment of acne scar in Asians.
* Study hypothesis

1. Reduction in acne scars based on blinded evaluation of before photos and the one and three month follow-up photos after four full face Ellipse Juvia with low density treatments with a fluency of 90-105 mJ/MTZ is statistically significant (5%).
2. The direct clinical blinded evaluated reduction in acne scars based on before photos and the patient in life, by the one and three month follow-up is statistically significant (5%)
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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Numbers of volunteers: 10 healthy men and women
• • Aged at least 30 year old
• • Skin type: 1 - 4
• • Degree of suntan: None - light
• • Skin condition: visible acne scars
• Exclusion Criteria:
• • Fitzpatrick skin types 5-6.
• • Patients with lesions with any clinical suspicion of being pre-cancerous or skin malignancies of any kind.
• • Patients with skin diseases associated with Koebner phenomena.
• • Patients who have used Botox or filler injection to the periorbital or perioral regions 12 months prior or during the study.
• • Patients who have used topical retinoids, AHA under prescription or Vitamin C, 3 months prior to or during the study.
• • Patients who are pregnant or who wish to become pregnant and lactating women.
• • Patients who have been exposed to sun within 2 week from date of treatment.
• • Patients prone to hypertrophic scars or keloids
• • Patients who have previously undergone laser resurfacing may not be suitable for yet another procedure.
• • Patients undergoing oral retinoid therapy for acne in the past 6 months.
• • Patients who suffer from any serious medical condition, including diabetes, bleeding diathesis, delayed wound healing or prednisolone intake.
• • Patients with wound infections (herpes, other) on the day of treatment.
• • Patients with moderate and severe inflammatory acne, Immunosuppressed patients, History of vitiligo.
• • Patients with unrealistic concerns/expectations and inability to do the appropriate post-operative care.