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Search / Trial NCT00763672

MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Sep 30, 2008

Trial Information

Current as of August 21, 2025

Completed

Keywords

Preeclampsia Hypertension Intra Uterine Growth Retardation Antiangiogenic Factor Prevention

ClinConnect Summary

We will measure plasmatic sFlt-1 level between 25 and 28 weeks of gestation and flow velocity of uterine arteries by Doppler (22 - 26 weeks of gestation) in primipara. Patients will be stratified according to the results of the uterine artery Doppler measurement, and then randomized in two groups A and B. In group A, sFlt-1 concentration will be communicated to the obstetrician (+ or -): the threshold of abnormally high plasmatic concentration of sFlt-1 is 957 ng/mL. In patients with a high plasmatic concentration of sFlt-1 (+), the pregnancy will be closely monitored including repeated cli...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Pregnant womenAge ≥ 18 years
  • Followed in our center before the 28th week of gestation
  • Under social security coverage
  • Signed informed consent
  • Exclusion Criteria:
  • Age \< 18 years
  • Followed in our center after the 28th week of gestation
  • No social security coverage
  • Refusal to be included

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Paris, , France

Patients applied

0 patients applied

Trial Officials

Nadia BERKANE, MD

Principal Investigator

Assistance Publique - Hôpitaux de Paris

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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