Establish and Characterize an Acute HIV Infection Cohort in a High Risk Population

Launched by SEARCH RESEARCH FOUNDATION · Nov 21, 2008

Keywords

ClinConnect Summary

**Trial Summary: Understanding Acute HIV Infection**

This clinical trial aims to learn more about people who have recently been infected with HIV, focusing on their health, behaviors, and immune responses. Researchers want to gather information on various aspects, such as the demographic details of participants (like age and behavior that might increase their risk of HIV), how HIV affects the brain, and the immune system's response during this early stage of infection. They will also explore the willingness of participants to help track their sexual contacts for counseling and testing, as well as study changes in T cells (a type of immune cell) in the gut.

To participate in this trial, you need to be over 18 years old and have a confirmed recent HIV infection. It’s important to understand the study and provide consent, which can be done even if you cannot read by having a staff member assist you. If you join, you'll undergo follow-ups throughout the study, and your information will contribute to future research on HIV. This trial is currently recruiting participants of all genders, so if you meet the criteria, you could play a vital role in helping us understand and combat HIV.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age \>18 years old
• • 2. Have protocol-defined acute HIV-1 infection (Tested 4th generation HIV EIA negative and NAT positive or tested 4th generation HIV EIA positive, negative by less sensitive EIA and NAT positive)
• • 3. Understand the study and sign informed consent form. Persons who cannot read will have the consent form read to them by a study staff and they can give informed consent by using thumb print.
• • 4. Availability for follow-up for the planned study duration
• Exclusion Criteria:
• • 1. Persons who have a history of a medical or psychiatric disorder by investigator's interview and physical examination according to standard practices, that in the judgment of the investigator(s), would interfere with or serve as a contraindication to adherence to the study protocol or ability to give informed consent.
• • 2. Female participants who are pregnant at the time of screening