Chinese Medicine Therapy on Menopausal Symptoms

Launched by THE UNIVERSITY OF HONG KONG · Nov 28, 2008

Keywords

ClinConnect Summary

This is a double-blind randomized placebo-controlled clinical trial to evaluate whether a Chinese medicine formula (Erxian Decoction) is effective in alleviating menopausal symptoms. This study will be conducted in Queen Mary Hospital and Chinese Medicine Clinic cum Training and Research Centers of the University of Hong Kong (Sassoon Road and Central). Women will be recruited from the general population by advertisements and promotion through media coverage.108 Chinese women with menopausal symptoms will be recruited and randomized into two groups.One is treatment group with 12 weeks of Er...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Chinese women aged 45 to 55 years old
• • 2. having irregular menstrual cycles (≥3 months) indicating perimenopausal status or with cessation of menstrual period for at least three months within the previous 12 months
• • 3. Total scores of Menopause Rating Scale≥28 indicating the menopausal symptoms are moderate or severe
• • 4. Not having used HRT or Chinese Medicine for at least 3 months prior to entry into the study
• • 5. Willing to give informed ,written consent to participate in the clinical study
• Exclusion Criteria:
• • 1. Taking hormones or medications, which could affect the vasomotoric symptoms
• • 2. Having chronic illness, such as gastrointestinal, renal or liver disease, diabetes mellitus requiring treatment, uncontrolled hypertension
• • 3. Having serious diseases, such as cancer, autoimmune system diseases, thrombosis and thrombophlebitis
• • 4. Consuming alcohol, or taking psychiatric or psychotherapeutic drugs