Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Major Abdominal Surgery

Launched by PFIZER · Jan 22, 2009

Keywords

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • Patient undergoing major abdominal surgery (Biliary strictures, Pancreatico-duodenectomy, Esophagectomy, Total proctocolectomy, Hemicolectomy, Gastrectomy, Other major abdominal surgeries with similar expected blood loss)
• Exclusion Criteria:
• • Patients with a platelet count less than 100, 000/mm3 or history of thrombocytopenia.
• • Patients with known coagulopathy.
• • Patients with anemia (hemoglobin levels less than 8 mg/dl)
• • Patients with documented DVT or PE at screening or in past three months.
• • Patients with any associated major illness (e.g., severe cardiac or respiratory disease).
• • Anticoagulants (other than LMWH or heparin in prophylactic doses to prevent deep vein thrombosis), direct thrombin inhibitors or thrombolytic therapy administered or completed within last week