Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding
Launched by KAOHSIUNG MEDICAL UNIVERSITY CHUNG-HO MEMORIAL HOSPITAL · Mar 12, 2009
Trial Information
Current as of August 22, 2025
Unknown status
Keywords
ClinConnect Summary
Proton pump inhibitor (PPI) is the drug of choice used in patients with non-variceal upper gastrointestinal tract bleeding (UGIB). Intravenous (IV) PPI is more commonly used than oral form when overt bleeding occurs. Previous study has revealed that oral rabeprazole and IV omeprazole achieved similar intragastric pH elevation. It's probable that oral form and IV PPI provide equal efficacy in treating mild to moderate UGIB patients.
This study aims to compare the effect of three-day oral rabeprazole and iv omeprazole on bleeding control in patients with mild to moderate non-variceal UGIB. T...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • moderate to mild upper gastrointestinal peptic ulcer bleeding
- Exclusion Criteria:
- • shock
- • liver cirrhosis
- • uremia
- • severe UGI bleeding
About Kaohsiung Medical University Chung Ho Memorial Hospital
Kaohsiung Medical University Chung-Ho Memorial Hospital is a leading healthcare institution in Taiwan, dedicated to advancing medical research and improving patient care through innovative clinical trials. As a prominent sponsor, the hospital leverages its extensive expertise in various medical disciplines, state-of-the-art facilities, and a multidisciplinary team of professionals to conduct rigorous clinical studies. Committed to ethical standards and patient safety, the hospital collaborates with academic institutions and industry partners to facilitate groundbreaking research that contributes to the global medical community and enhances treatment options for diverse patient populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kaohsiung, , Taiwan
Patients applied
Trial Officials
Chien-Yu Lu, MD
Principal Investigator
Kaohsiung Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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