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Search / Trial NCT00872495

Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

Launched by LAHEY CLINIC · Mar 27, 2009

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Urothelial Cancer Cancer Bladder Neoplasms Urinary Bladder Cancer

ClinConnect Summary

This clinical trial is studying whether analyzing DNA and protein found in urine can help detect urothelial cancer, which affects the bladder and kidneys. The researchers want to see if this urine test can provide information about how the cancer might behave, including whether it could come back after treatment. The trial is currently looking for participants, including those who are about to have surgery for bladder cancer or who are in follow-up for recurrent disease. They also need a control group of people with no evidence of bladder cancer.

To be eligible for the trial, participants must be at least 18 years old and scheduled for certain procedures like nephroureterectomy or cystectomy. If you join the study, you'll provide urine samples, which will be tested to see if this non-invasive method can effectively identify urothelial cancer. This could potentially lead to better ways of monitoring and treating the disease. If you're interested and meet the criteria, consider discussing this opportunity with your healthcare provider.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients scheduled to have a nephroureterectomy, cystectomy, cytoscopy (newly diagnosed bladder cancer and those with recurrent disease in follow up)
  • Control Group: No known evidence of bladder cancer-one urine sample
  • \> than 18 years of age
  • Exclusion Criteria:
  • \< than 18 years of age

About Lahey Clinic

Lahey Clinic, a leading non-profit healthcare organization, is dedicated to advancing medical research and improving patient care through innovative clinical trials. With a strong emphasis on patient-centered approaches, Lahey Clinic collaborates with multidisciplinary teams of healthcare professionals to conduct rigorous research across various therapeutic areas. Their commitment to ethical standards and regulatory compliance ensures the safety and well-being of participants, while contributing valuable insights to the medical community. By fostering a culture of excellence and collaboration, Lahey Clinic aims to translate research findings into effective treatments that enhance the quality of life for patients.

Locations

Burlington, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Kimberly Rieger-Christ, PhD

Principal Investigator

Lahey Clinic, Inc.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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