Study of Stored Tumor Samples in Young Patients With Brain Tumors
Launched by ST. JUDE CHILDREN'S RESEARCH HOSPITAL · May 9, 2009
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is examining stored tumor samples from young patients with brain tumors. The goal is to learn more about the changes in DNA that happen in these tumors and to identify specific markers that might help doctors understand cancer better. By studying these samples, researchers hope to find new ways to treat and diagnose brain tumors in children and young adults.
To be eligible for this study, participants should be under 40 years old at the time of their initial diagnosis and have a tumor in the brain or spinal cord, including specific types like medulloblastoma and gliomas. If a patient is selected for the study, they can expect their tumor samples to be analyzed in a laboratory setting, which may help advance our understanding of brain tumors and improve future treatments. It's important to note that this study is currently open for recruitment, so interested families can reach out for more information.
Gender
ALL
Eligibility criteria
- • Inclusion Criteria
- • Tumor may be primary, progressive or recurrent CNS tumor including brain and/or spine. All tumor types will be included with a focus on medulloblastoma, HGNET, CNS embryonal tumors, gliomas, ependymoma, CPC and ATRT tumors. Low grade gliomas are currently very challenging to culture and implant but if techniques mature these will also be included. Although rare, patients with ATRT may present with a primary renal and CNS tumor. In these instances samples will be collected from both the kidney and CNS tumor for analysis if available.
- • Tumor may be collected at surgery prior to histologic confirmation
- • Age less than 40 years at the time of initial diagnosis.
- • Enrollment in the current version of the institution's banking protocol
- • Exclusion Criteria
- • Diagnosis of tumor outside the central nervous system.
- • Age greater than or equal to 40 years at the time of diagnosis
About St. Jude Children's Research Hospital
St. Jude Children's Research Hospital is a premier pediatric research institution dedicated to advancing the treatment and understanding of catastrophic diseases in children, particularly cancer and other life-threatening conditions. Renowned for its innovative clinical trials and cutting-edge research, St. Jude integrates patient care with scientific discovery to develop new therapies and improve outcomes for young patients. The hospital is committed to ensuring that no family receives a bill for treatment, travel, housing, or food, fostering a holistic approach to pediatric care. Through collaboration with global research networks, St. Jude aims to share its findings and expertise to enhance treatment options worldwide, making significant strides in pediatric medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Memphis, Tennessee, United States
Patients applied
Trial Officials
Amar Gajjar, MD
Principal Investigator
St. Jude Children's Research Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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